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Antibody detects endogenous levels of total RANBP17.
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ran-binding protein 17
Gene Aliases: RANBP17; RGD1562576
UniProt ID: (Human) Q9H2T7, (Mouse) Q99NF8
Entrez Gene ID: (Human) 64901, (Rat) 303029, (Mouse) 66011
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