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          • Primary Antibodies ›
          • RANGRF Antibodies

          Invitrogen

          RANGRF Polyclonal Antibody

          View all (5) RANGRF antibodies

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          Datasheet
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          Cite RANGRF Polyclonal Antibody

          • Antibody Testing Data (5)
          RANGRF Antibody in Immunocytochemistry (ICC/IF)
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          RANGRF Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          RANGRF Antibody (PA5-118236) in ICC/IF

          Immunofluorescence staining of RANGRF in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with RANGRF Polyclonal Antibody (Product # PA5-118236, 1:100) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RANGRF Antibody in Immunocytochemistry (ICC/IF)
          RANGRF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RANGRF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RANGRF Antibody in Western Blot (WB)
          RANGRF Antibody in Immunoprecipitation (IP)

          Product Details

          PA5-118236

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          Immunoprecipitation (IP)

          1-5 µL/mg of lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          E. coli-derived Human RANGRF fragment

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Antigen affinity chromatography, Protein A

          Storage buffer

          PBS, pH 7

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Wet ice

          RRID

          AB_2902836

          Target Information

          May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: MOG1 homolog; Ran guanine nucleotide release factor; Ran-binding protein MOG1; RanGNRF

          View more View less

          Gene Aliases: HSPC165; HSPC236; MDS5; MOG1; RANGNRF; RANGRF

          View more View less

          UniProt ID: (Human) Q9HD47

          View more View less

          Entrez Gene ID: (Human) 29098

          View more View less

          Function(s)
          guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity Ran GTPase binding protein transporter activity sodium channel regulator activity ion channel binding
          Process(es)
          regulation of heart rate regulation of membrane depolarization ER to Golgi vesicle-mediated transport protein exit from endoplasmic reticulum regulation of membrane potential positive regulation of GTPase activity positive regulation of establishment of protein localization to plasma membrane regulation of membrane depolarization during cardiac muscle cell action potential regulation of sodium ion transmembrane transport positive regulation of protein localization to cell surface regulation of sodium ion transmembrane transporter activity
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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