Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
67174-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E7G11
Immunogen
RAP1B Fusion Protein Ag29212
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GTP-binding protein smg p21B; Ras family small GTP binding protein RAP1B; RAS related protein 1b; Ras-related protein Rap-1b; RAS-related protein RAP1B; small GTP binding protein
Gene Aliases: 2810443E11Rik; K-REV; OK/SW-cl.11; RAL1B; RAP1B
UniProt ID: (Human) P61224, (Rat) Q62636, (Mouse) Q99JI6
Entrez Gene ID: (Human) 5908, (Rat) 171337, (Mouse) 215449
small GTPase mediated signal transduction
metabolic process
cell proliferation
microvillus assembly
Rap protein signal transduction
negative regulation of calcium ion-dependent exocytosis
establishment of endothelial barrier
positive regulation of ERK1 and ERK2 cascade
cellular response to cAMP
regulation of cell junction assembly
regulation of establishment of cell polarity
negative regulation of synaptic vesicle exocytosis
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support