Proteintech

RAP1GDS1 Polyclonal Antibody

RAP1GDS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

RAP1GDS1 Antibody (10377-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 10377-1-AP ( RAP1GDS1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RAP1GDS1 Antibody in Immunoprecipitation (IP)

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Product Details

10377-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAP1GDS1 Fusion Protein Ag0230 (176-406 aa encoded by BC001851)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: QLINMGVIP TLVKLLGIHC QNAALTEMCL VAFGNLAELE SSKEQFASTN IAEELVKLFK KQIEHDKREM IFEVLAPLAE NDAIKLQLVE AGLVECLLEI VQQKVDSDKE DDITELKTGS DLMVLLLLGD ESMQKLFEGG KGSVFQRVLS WIPSNNHQLQ LAGALAIANF ARNDANCIHM VDNGIVEKLM DLLDRHVEDG NVTVQHAALS ALRNLAIPVI NKAKMLSAGV TE (176-406 aa encoded by BC001851)

Target Information

The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 ).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age.

Communications biology

Xiong Y,Cheng Q,Li Y,Han Y,Sun X,Liu L

Sat Apr 15 00:00:00 UTC 2023

Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.

Microbiology spectrum

Zhang B,Fan M,Fan J,Luo Y,Wang J,Wang Y,Liu B,Sun Y,Zhao Q,Hiscox JA,Nan Y,Zhou EM

Wed Feb 23 00:00:00 UTC 2022

Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization.

Microbiology spectrum

Zhang B,Fan M,Fan J,Luo Y,Wang J,Wang Y,Liu B,Sun Y,Zhao Q,Hiscox JA,Nan Y,Zhou EM

Wed Feb 23 00:00:00 UTC 2022

SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.

Oncology letters

Liang JX,Gao W,Zeng XW,Cheng GP,Cai L,Tao KY,Yang X

Sun Nov 01 00:00:00 UTC 2020

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.

Nature genetics

Nissim S,Leshchiner I,Mancias JD,Greenblatt MB,Maertens O,Cassa CA,Rosenfeld JA,Cox AG,Hedgepeth J,Wucherpfennig JI,Kim AJ,Henderson JE,Gonyo P,Brandt A,Lorimer E,Unger B,Prokop JW,Heidel JR,Wang XX,Ukaegbu CI,Jennings BC,Paulo JA,Gableske S,Fierke CA,Getz G,Sunyaev SR,Wade Harper J,Cichowski K,Kimmelman AC,Houvras Y,Syngal S,Williams C,Goessling W

Sun Sep 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: Exchange factor smgGDS; Rap1 GTPase-GDP dissociation stimulator 1; RAP1, GTP-GDP dissociation stimulator 1; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein

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Gene Aliases: BC011279; GDS1; RAP1GDS1; SMGGDS

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UniProt ID: (Human) P52306, (Mouse) E9Q912

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Entrez Gene ID: (Human) 5910, (Mouse) 229877

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Function(s)

GTPase activator activity protein binding molecular_function

Process(es)

vascular smooth muscle contraction myosin filament assembly negative regulation of endoplasmic reticulum calcium ion concentration positive regulation of GTPase activity positive regulation of mitochondrial calcium ion concentration small GTPase mediated signal transduction

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RAP1GDS1 Polyclonal Antibody

RAP1GDS1 Antibody (10377-1-AP) in IHC (P)

Product Details

10377-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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