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Proteintech
RAP2B Polyclonal Antibody
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Product Details
16266-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RAP2B Fusion Protein Ag9331 (1-183 aa encoded by BC012362)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MREYKVVVL GSGGVGKSAL TVQFVTGSFI EKYDPTIEDF YRKEIEVDSS PSVLEILDTA GTEQFASMRD LYIKNGQGFI LVYSLVNQQS FQDIKPMRDQ IIRVKRYERV PMILVGNKVD LEGEREVSYG EGKALAEEWS CPFMETSAKN KASVDELFAE IVRQMNYAAQ PNGDEGCCSA CVIL (1-183 aa encoded by BC012362)
Target Information
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ras-related protein Rap-2b; small GTP binding protein
Gene Aliases: 4021402C18Rik; AA408554; RAP2B
UniProt ID: (Human) P61225, (Rat) P61227, (Mouse) P61226
Entrez Gene ID: (Human) 5912, (Rat) 170923, (Mouse) 74012
microvillus assembly
platelet activation
negative regulation of cell migration
positive regulation of protein autophosphorylation
Rap protein signal transduction
regulation of protein tyrosine kinase activity
platelet aggregation
establishment of endothelial intestinal barrier
signal transduction
small GTPase mediated signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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