Abnova

RAPGEF3 Polyclonal Antibody, MaxPab™

View all (21) RAPGEF3 antibodies

Promotion

View available promotion(s)

Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

H00010411-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunocytochemistry (ICC/IF)

10-100 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RAPGEF3 (NP_006096.2, 1 a.a. approximately 881 a.a) full-length human protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MVLRRMHRPR SCSYQLLLEH QRPSCIQGLR WTPLTNSEES LDFSESLEQA STERVLRAGR QLHRHLLATC PNLIRDRKYH LRLYRQCCSG RELVDGILAL GLGVHSRSQV VGICQVLLDE GALCHVKHDW AFQDRDAQFY RFPGPEPEPV GTHEMEEELA EAVALLSQRG PDALLTVALR KPPGQRTDEE LDLIFEELLH IKAVAHLSNS VKRELAAVLL FEPHSKAGTV LFSQGDKGTS WYIIWKGSVN VVTHGKGLVT TLHEGDDFGQ LALVNDAPRA ATIILREDNC HFLRVDKQDF NRIIKDVEAK TMRLEEHGKV VLVLERASQG AGPSRPPTPG RNRYTVMSGT PEKILELLLE AMGPDSSAHD PTETFLSDFL LTHRVFMPSA QLCAALLHHF HVEPAGGSEQ ERSTYVCNKR QQILRLVSQW VALYGSMLHT DPVATSFLQK LSDLVGRDTR LSNLLREQWP ERRRCHRLEN GCGNASPQMK ARNLPVWLPN QDEPLPGSSC AIQVGDKVPY DICRPDHSVL TLQLPVTASV REVMAALAQE DGWTKGQVLV KVNSAGDAIG LQPDARGVAT SLGLNERLFV VNPQEVHELI PHPDQLGPTV GSAEGLDLVS AKDLAGQLTD HDWSLFNSIH QVELIHYVLG PQHLRDVTTA NLERFMRRFN ELQYWVATEL CLCPVPGPRA QLLRKFIKLA AHLKEQKNLN SFFAVMFGLS NSAISRLAHT WERLPHKVRK LYSALERLLD PSWNHRVYRL ALAKLSPPVI PFMPLLLKDM TFIHEGNHTL VENLINFEKM RMMARAARML HHCRSHNPVP LSPLRSRVSH LHEDSQVARI STCSEQSLST RSPASTWAYV QQLKVIDNQR ELSRLSRELE P

Target Information

Gene ontology (GO) annotation includes small GTPase mediated signal transduction. Target protein binds cAMP and activates the Ras superfamily guanine nucleotide binding protein (Rap1A)in a PKA-independent manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 9330170P05Rik; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I; EPAC 1; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; MGC21410; Rap guanine nucleotide exchange factor (GEF) 3; Rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

View more View less

Gene Aliases: 2310016P22Rik; 9330170P05Rik; bcm910; CAMP-GEFI; CGEF1; EPAC; EPAC1; HSU79275; RAPGEF3

View more View less

UniProt ID: (Human) O95398, (Mouse) Q8VCC8

View more View less

Entrez Gene ID: (Human) 10411, (Mouse) 223864

View more View less

Function(s)
guanyl-nucleotide exchange factor activity protein binding Rap guanyl-nucleotide exchange factor activity protein domain specific binding cAMP binding ion channel binding nucleotide binding cAMP-dependent protein kinase regulator activity
Process(es)
angiogenesis regulation of protein phosphorylation positive regulation of protein phosphorylation small GTPase mediated signal transduction positive regulation of smooth muscle cell migration Rap protein signal transduction positive regulation of ATPase activity negative regulation of collagen biosynthetic process positive regulation of peptidyl-serine phosphorylation negative regulation of syncytium formation by plasma membrane fusion intracellular signal transduction positive regulation of GTPase activity positive regulation of angiogenesis positive regulation of cell size positive regulation of transcription from RNA polymerase II promoter positive regulation of protein export from nucleus positive regulation of binding positive regulation of stress fiber assembly positive regulation of calcium ion transport positive regulation of syncytium formation by plasma membrane fusion negative regulation of cell death establishment of endothelial barrier cellular response to cAMP positive regulation of protein acetylation regulation of actin cytoskeleton reorganization positive regulation of actin cytoskeleton reorganization signal transduction brain development cell proliferation negative regulation of cardiac muscle cell apoptotic process cAMP-mediated signaling spinal cord development positive regulation of cAMP catabolic process response to nicotine cellular response to drug regulation of insulin secretion artery development cellular response to transforming growth factor beta stimulus liver regeneration positive regulation of GTP binding positive regulation of calcium ion transmembrane transport positive regulation of hydrogen:potassium-exchanging ATPase activity cellular response to L-dopa dorsal root ganglion development regulation of histone H3-K9 acetylation
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support