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Invitrogen
RAPGEF4 Polyclonal Antibody
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Product Details
PA5-56019
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RAPGEF4. Recombinant protein control fragment (Product #RP-95156).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646310
Product Specific Information
Immunogen sequence: VIYGKGVVCT LHEGDDFGKL ALVNDAPRAA SIVLREDNCH FLRVDKEDFN RILRDVEANT VRLKEHDQDV LVLEKVPAGN RASNQGNSQP QQKYTVMSGT PEKILEHFLE TIRLEATLNE ATDSVLNDFI MMHCVFMPNT QLC
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
Target Information
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; EPAC 2; Exchange factor directly activated by cAMP 2; Exchange protein directly activated by cAMP 2; gefii; putative protein product of Nbla00496; Rap guanine nucleotide exchange factor (GEF) 4; Rap guanine nucleotide exchange factor 4; RAP guanine-nucleotide-exchange factor (GEF) 4
Gene Aliases: CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496; RAPGEF4
UniProt ID: (Human) Q8WZA2
Entrez Gene ID: (Human) 11069
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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