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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • RAPSN Antibodies

          Invitrogen

          RAPSN Monoclonal Antibody (1234)

          3 Published Figures
          9 References
          View all (7) RAPSN antibodies

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          Datasheet
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          Datasheet
          Protocols
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          Cite RAPSN Monoclonal Antibody (1234)

          • Published Figures (3)
          RAPSN Antibody in Immunocytochemistry (ICC/IF)
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          RAPSN Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          RAPSN Antibody (MA1-746) in ICC/IF

          Molecular and cellular neurosciences 2008 - Published figure using RAPSN monoclonal antibody (Product # MA1-746) in Immunocytochemistry {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RAPSN Antibody in Immunocytochemistry (ICC/IF)
          RAPSN Antibody in Immunohistochemistry (IHC)
          RAPSN Antibody in Western Blot (WB)

          Product Details

          MA1-746

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.5 µg/mL
          View 2 publications 2 publications

          Immunohistochemistry (IHC)

          -
          View 4 publications 4 publications

          Immunocytochemistry (ICC/IF)

          2 µg/mL
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Amphibian, Chicken, Fish, Mouse, Rat

          Published species

          Amphibian, Avian, Chordate, Mouse, Rat, Xenopus

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1234

          Immunogen

          Whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS with 1mg/mL BSA

          Contains

          0.05% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2177611

          Product Specific Information

          MA1-746 detects rapysn from mouse, rat, chicken, amphibian and fish samples.

          MA1-746 has been used in immunochemistry procedures using cryosections, immunocytochemistry, immunofluorescence and Western Blot procedures. By Western blot, this antibody detects a 48 kDa protein representing rapsyn from Torpedo californica electrocyte cell extracts.

          The MA1-746 immunogen is whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.

          Target Information

          This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 43 kDa postsynaptic protein; 43 kDa receptor-associated protein of the synapse; 43kDa acetylcholine receptor-associated protein; Acetylcholine receptor-associated 43 kDa protein; CMS1D; CMS1E; MGC3597; RAPsyn; receptor-associated protein of the synapse, 43 kDa; receptor-associated protein of the synapse, 43kD

          View more View less

          Gene Aliases: 43kDa; Nraps; Raps; RAPSN; rapsyn

          View more View less

          UniProt ID: (Chicken) O42393, (Mouse) P12672

          View more View less

          Entrez Gene ID: (Chicken) 395986, (Rat) 362161, (Mouse) 19400

          View more View less

          Function(s)
          zinc ion binding acetylcholine receptor binding ionotropic glutamate receptor binding protein anchor metal ion binding
          Process(es)
          synaptic transmission, cholinergic positive regulation of neuron apoptotic process skeletal muscle acetylcholine-gated channel clustering positive regulation of neuromuscular synaptic transmission regulation of postsynaptic membrane organization chemical synaptic transmission
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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