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Abnova
RARRES2 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 2
RARRES2 Antibody (H00005919-D01P) in WB
Western Blot analysis of RARRES2 expression in transfected 293T cell line (H00005919-T01) by RARRES2 MaxPab polyclonal antibody.
Lane 1: RARRES2 transfected lysate(18.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: RARRES2 transfected lysate(18.60 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00005919-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RARRES2 (NP_002880.1, 1 a.a. approximately 163 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MRRLLIPLAL WLGAVGVGVA ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFSKAL PRS
Target Information
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chemerin; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; Retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG-2; TIG2HP10433
Gene Aliases: 0610007L05Rik; AI303516; HP10433; RARRES2; TIG2
UniProt ID: (Human) Q99969, (Mouse) Q9DD06
Entrez Gene ID: (Human) 5919, (Mouse) 71660
retinoid metabolic process
positive regulation of protein phosphorylation
chemotaxis
defense response
inflammatory response
positive regulation of macrophage chemotaxis
cell differentiation
positive regulation of fat cell differentiation
embryonic digestive tract development
brown fat cell differentiation
positive regulation of chemotaxis
regulation of lipid catabolic process
positive regulation of glucose import in response to insulin stimulus
in utero embryonic development
platelet degranulation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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