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Product Details
PA5-57248
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RASA2. Recombinant protein control fragment (Product #RP-96380).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646323
Product Specific Information
Immunogen sequence: SLSKSKSSFK ETFMCEFFKM FQEEGYIIAV KKFLDEISST ETKESSGTSE PVHLKEGEMY KRAQGRTRIG K
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.
Target Information
The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CM-AVM; CMAVM; DKFZp434N071; GAP; GAP1m; GTPase-activating protein 1m; GTPase-activating protein of RAS; p120GAP; p120RASGAP; PKWS; Ras GTPase-activating protein 2; RASA
Gene Aliases: GAP1M; RASA2; RASGAP
UniProt ID: (Human) Q15283
Entrez Gene ID: (Human) 5922
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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