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Proteintech
RASSF7 Polyclonal Antibody
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Product Details
21753-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RASSF7 Fusion Protein Ag16123 (91-292 aa encoded by BC106921)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LAGRPSSDS CPPPERCLIR ASLPVKPRAA LGCEPRKTLT PEPAPSLSRP GPAAPVTPTP GCCTDLRGLE LRVQRNAEEL GHEAFWEQEL RREQAREREG QARLQALSAA TAEHAARLQA LDAQARALEA ELQLAAEAPG PPSPMASATE RLHQDLAVQE RQSAEVQGSL ALVSRALEAA ERALQAQAQE LEELNRELRQ CNL (91-292 aa encoded by BC106921)
Target Information
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HRAS1-related cluster protein 1; HRAS1-related cluster-1; MGC126069; MGC126070; Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Ras association (RalGDS/AF-6) domain family 7; Ras association domain-containing protein 7
Gene Aliases: C11orf13; HRAS1; HRC1; RASSF7; RGD1306244
UniProt ID: (Human) Q02833
Entrez Gene ID: (Human) 8045, (Rat) 293623
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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