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This antibody is predicted to react with bovine and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carcinoma-associated protein HOJ-1; HoJ-1; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; Ras association domain-containing protein 8
Gene Aliases: C12orf2; HOJ1; RASSF8
UniProt ID: (Human) Q8NHQ8
Entrez Gene ID: (Human) 11228
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