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Abnova
RASSF8 Monoclonal Antibody (2G1)
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Product Details
H00011228-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2G1
Immunogen
RASSF8 (NP_009142, 40 a.a. approximately 137 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: YTLIEKWRDT ERHLAPHENP IISLNKWGQY ASDVQLILRR TGPSLSERPT SDSVARIPER TLYRQSLPPL AKLRPQIDKS IKRREPKRKS LTFTGGAK
Target Information
RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carcinoma-associated protein HOJ-1; Carcinoma-associated protein HOJ-1 homolog; HoJ-1; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; Ras association (RalGDS/AF-6) domain family 8; Ras association domain-containing protein 8
Gene Aliases: 5133400D11Rik; AA815821; AW123240; C12orf2; HOJ1; mHoj-1; RASSF8; RGD1308820
UniProt ID: (Human) Q8NHQ8, (Mouse) Q8CJ96
Entrez Gene ID: (Human) 11228, (Mouse) 71323, (Rat) 312846
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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