Proteintech

RBCK1 Polyclonal Antibody

View all (13) RBCK1 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (3)

RBCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RBCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 3

RBCK1 Antibody (26367-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human placenta tissue slide using 26367-1-AP (RBCK1 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RBCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RBCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RBCK1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

RBCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human placenta tissue slide using 26367-1-AP (RBCK1 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RBCK1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human placenta tissue slide using 26367-1-AP (RBCK1 antibody) at dilution of 1:200 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RBCK1 Antibody in Immunoprecipitation (IP) — IP result of anti-RBCK1 (IP:26367-1-AP, 4ug; Detection:26367-1-AP 1:300) with human placenta tissue lysate 1520ug.

Product Details

26367-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 7 publications 7 publications

Immunohistochemistry (IHC)

-

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RBCK1 Fusion Protein Ag24405 (225-500 aa encoded by BC015219)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EERARLAGE EEALRQYQQR KQQQQEGNYL QHVQLDQRSL VLNTEPAECP VCYSVLAPGE AVVLRECLHT FCRECLQGTI RNSQEAEVSC PFIDNTYSCS GKLLEREIKA LLTPEDYQRF LDLGISIAEN RSAFSYHCKT PDCKGWCFFE DDVNEFTCPV CFHVNCLLCK AIHEQMNCKE YQEDLALRAQ NDVAARQTTE MLKVMLQQGE AMRCPQCQIV VQKKDGCDWI RCTVCHTEIC WVTKGPRWGP GGPGDTSGGC RCRVNGIPCH PSCQNCH (225-500 aa encoded by BC015219 )

Target Information

RBCK1 encodes a protein that is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.

Oncogene

Wang Y,Peng M,Zhong Y,Xiong W,Zhu L,Jin X

Wed Mar 01 00:00:00 UTC 2023

The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.

Oncogene

Wang Y,Peng M,Zhong Y,Xiong W,Zhu L,Jin X

Wed Mar 01 00:00:00 UTC 2023

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

RBCK1 regulates the progression of ER-positive breast cancer through the HIF1α signaling.

Cell death & disease

Niu Z,Fan J,Chen F,Yang H,Li X,Zhuang T,Guo C,Cao Q,Zhu J,Wang H,Huang Q

Tue Dec 06 00:00:00 UTC 2022

Regulation of PTEN and ovarian cancer progression by an E3 ubiquitin ligase RBCK1.

Human cell

Wang G,Zhuang Z,Shen S,Yang F,Jiang Z,Liu Z,Wang T,Hua L

Sun May 01 00:00:00 UTC 2022

Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.

Frontiers in immunology

Fu L,Bao J,Li J,Li Q,Lin H,Zhou Y,Li J,Yan Y,Langston ME,Sun T,Guo S,Zhou X,Chen Y,Liu Y,Zhao Y,Lu J,Huang Y,Chen W,Chung BI,Luo J

Tue Oct 18 00:00:00 UTC 2022

Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.

Frontiers in immunology

Fu L,Bao J,Li J,Li Q,Lin H,Zhou Y,Li J,Yan Y,Langston ME,Sun T,Guo S,Zhou X,Chen Y,Liu Y,Zhao Y,Lu J,Huang Y,Chen W,Chung BI,Luo J

Tue Oct 18 00:00:00 UTC 2022

RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.

Cell communication and signaling : CCS

Li Z,Su P,Ding Y,Gao H,Yang H,Li X,Yang X,Xia Y,Zhang C,Fu M,Wang D,Zhang Y,Zhuo S,Zhu J,Zhuang T

Mon Oct 24 00:00:00 UTC 2022

RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.

Cell communication and signaling : CCS

Li Z,Su P,Ding Y,Gao H,Yang H,Li X,Yang X,Xia Y,Zhang C,Fu M,Wang D,Zhang Y,Zhuo S,Zhu J,Zhuang T

Mon Oct 24 00:00:00 UTC 2022

Polyglucosan body myopathy 1 may cause cognitive impairment: a case report from China.

BMC musculoskeletal disorders

Chen L,Wang N,Hu W,Yu X,Yang R,Han Y,Yan Y,Nian N,Sha C

Thu Jan 07 00:00:00 UTC 2021

RBCK1 promotes p53 degradation via ubiquitination in renal cell carcinoma.

Cell death & disease

Yu S,Dai J,Ma M,Xu T,Kong Y,Cui C,Chi Z,Si L,Tang H,Yang L,Sheng X,Guo J

Fri Mar 15 00:00:00 UTC 2019

A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis.

Archives of oral biology

Sun S,Li F,Liu Y,Qu H,Wong SW,Zeng L,Yu M,Feng H,Liu H,Han D

Wed May 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: HBV-associated factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; Hepatitis B virus X-associated protein 4; HOIL-1; RanBP-type and C3HC4-type zinc finger-containing protein 1; RBCC protein interacting with PKC1; RING finger protein 54; RING-type E3 ubiquitin transferase HOIL-1; ubiquitin conjugating enzyme 7 interacting protein 3; Ubiquitin-conjugating enzyme 7-interacting protein 3

View more View less

Gene Aliases: C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1; RBCK1; RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4

View more View less

UniProt ID: (Human) Q9BYM8

View more View less

Entrez Gene ID: (Human) 10616

View more View less

double-stranded DNA binding ubiquitin-protein transferase activity protein kinase C binding protein binding zinc ion binding ligase activity ubiquitin binding

protein polyubiquitination I-kappaB kinase/NF-kappaB signaling regulation of tumor necrosis factor-mediated signaling pathway viral process negative regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB signaling proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of transcription from RNA polymerase II promoter T cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity negative regulation of necroptotic process protein linear polyubiquitination positive regulation of extrinsic apoptotic signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support