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Abnova
RBM15 Polyclonal Antibody, MaxPab™
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Product Details
H00064783-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RBM15 (AAI03661.1, 1 a.a. approximately 544 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSHRAKLAMS GKIIIRNPIK IGYGKATPTT RLWVGGLGPW VPLAALAREF DRFGTIRTID YRKGDSWAYI QYESLDAAHA AWTHMRGFPL GGPDRRLRVD FADTEHRYQQ QYLQPLPLTH YELVTDAFGH RAPDPLRGAR DRTPPLLYRD RDRDLYPDSD WVPPPPPVRE RSTRTAATSV PAYEPLDSLD RRRDGWSLDR DRGDRDLPSS RDQPRKRRLP EESGGRHLDR SPESDRPRKR HCAPSPDRSP ELSSSRDRYN SDNDRSSRLL LERPSPIRDR RGSLEKSQGD KRDRKNSASA ERDRKHRTTA PTEGKSPLKK EDRSDGSAPS TSTASSKLKS PSQKQDGGTA PVASASPKLC LAWQGMLLLK NSNFPSNMHL LQGDLQVASS LLVEGSTGGK VAQLKITQRL RLDQPKLDEV TRRIKVAGPN GYAILLAVPG SSDSRSSSSS AASDTATSTQ RPLRNLVSYL KQKQAAGVIS LPVGGNKDKE NTGVLHAFPP CEFSQQFLDS PAKALAKSEE DYLVMIIVRA KLVEQRMKIW NSKL
Target Information
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: one twenty two protein; one twenty-two; One-twenty two protein 1; RNA binding motif protein 15; RNA-binding motif protein 15; RNA-binding protein 15
Gene Aliases: OTT; OTT1; RBM15; SPEN
UniProt ID: (Human) Q96T37
Entrez Gene ID: (Human) 64783, (Rat) 684233
mRNA splicing, via spliceosome
patterning of blood vessels
positive regulation of transcription of Notch receptor target
viral process
negative regulation of myeloid cell differentiation
negative regulation of transcription, DNA-templated
spleen development
ventricular septum morphogenesis
placenta blood vessel development
negative regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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