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Proteintech
RBM5 Polyclonal Antibody
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Product Details
19930-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RBM5 Fusion Protein Ag13908 (1-350 aa encoded by BC002957)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGSDKRVSR TERSGRYGSI IDRDDRDERE SRSRRRDSDY KRSSDDRRGD RYDDYRDYDS PERERERRNS DRSEDGYHSD GDYGEHDYRH DISDERESKT IMLRGLPITI TESDIREMME SFEGPQPADV RLMKRKTGVS RGFAFVEFYH LQDATSWMEA NQKKLVIQGK HIAMHYSNPR PKFEDWLCNK CCLNNFRKRL KCFRCGADKF DSEQEVPPGT TESVQSVDYY CDTIILRNIA PHTVVDSIMT ALSPYASLAV NNIRLIKDKQ TQQNRGFAFV QLSSAMDASQ LLQILQSLHP PLKIDGKTIG VDFAKSARKD LVLSDGNRVS AFSVASTAIA AAQWSSTQSQ S (1-350 aa encoded by BC002957)
Target Information
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein G15; Putative tumor suppressor LUCA15; Renal carcinoma antigen NY-REN-9; RNA-binding motif protein 5; RNA-binding protein 5
Gene Aliases: D030069N10Rik; G15; H37; LUCA15; RBM5; RMB5
UniProt ID: (Human) P52756, (Mouse) Q91YE7, (Rat) B2GV05
Entrez Gene ID: (Human) 10181, (Mouse) 83486, (Rat) 300996
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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