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Abnova
RBM6 Polyclonal Antibody, MaxPab™
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Product Details
H00010180-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RBM6 (AAH46643.1, 1 a.a. approximately 601 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MIQDKEVTLE YVSSLDFWYC KRCKANIGGH RSSCSFCKNP REVTEAKQEL ITYPQPQKTS IPAPLEKQPN QPLRPADKEP EPRKREEGQE SRLGHQKREA ERYLPPSRRE GPTFRRDRER ESWSGETRQD GESKTIMLKR IYRSTPPEVI VEVLEPYVRL TTANVRIIKN RTGPMGHTYG FIDLDSHAEA LRVVKILQNL DPPFSIDGKM VAVNLATGKR RNDSGDHSDH MHYYQGKKYF RDRRGGGRNS DWSSDTNRQG QQSSSDCYIY DSATGYYYDP LAGTYYDPNT QQEVYVPQDP GLPEEEEIKE KKPTSQGKSS SKKEMSKRDG KEKKDRGVTR FQENASEGKA PAEDVFKKPL PPTVKKEESP PPPKVVNPLI GLLGEYGGDS DYEEEEEEEQ TPPPQPRTAQ PQKREEQTKK ENEEDKLTDW NKLACLLCRR QFPNKEVLIK HQQLSDLHKQ NLEIHRKIKQ SEQELAYLER REREGKFKGR GNDRREKLQS FDSPERKRIK YSRETDSDRK LVDKEDIDTS SKGGCVQQAT GWRKGTGLGY GHPGLASSEE AEGRMRGPSV GASGRTSKRQ SNETYRDAVR RVMFARYKEL D
Target Information
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ETK2; HEK2; Lung cancer antigen NY-LU-12; lung cancer protooncogene 11; Protein G16; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3; TYRO6
Gene Aliases: 3G2; DEF-3; DEF3; g16; HLC-11; NY-LU-12; RBM6
UniProt ID: (Human) P78332
Entrez Gene ID: (Human) 10180
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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