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Immunogen sequence: MNHLSLGTTG TIQSQDRIMI LHQLLCQYMT AAAPMQGTYI PQYTPVPPTA VSIEGVVADT SPQTVAPSSQ DTSGQQQQI
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RNA binding motif, single stranded interacting protein 3; RNA-binding motif, single-stranded-interacting protein 3; RNA-binding protein
Gene Aliases: RBMS3
UniProt ID: (Human) Q6XE24
Entrez Gene ID: (Human) 27303
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