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Invitrogen
RBMX Polyclonal Antibody
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RBMX Antibody (PA5-99433) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded RBMX in human Breast tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with RBMX polyclonal antibody (Product # PA5-99433) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-99433
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RBMX(Accession P38159), corresponding to amino acid residues N20-N70.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818366
Product Specific Information
Antibody detects endogenous levels of total hnRNP G.
Target Information
hnRNP G is a glycoprotein, which was originally identified as an autoantigen from German shepherd dogs with lupus-like syndrome. The gene encoding hnRNP G is located on chromosome Xq26 and is ubiquitously expressed. It contains one RNP-consensus RNA binding domain (RBD) and is related to RBMY, which is involved in spermatogenesis, and hnRNP G-T, which is a testis specific protein. All three proteins interact with Tra2b and therefore, are involved in pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Glycoprotein p43; Heterogeneous nuclear ribonucleoprotein G; hnRNP G; RNA binding motif protein, X chromosome; RNA-binding motif protein, X chromosome; RNA-binding motif protein, X chromosome retrogene; RNA-binding motif protein, X chromosome retrogene-like
Gene Aliases: hnRNP G; hnRNP-G; HNRNPG; HNRPG; MRXS11; RBMX; RBMXP1; RBMXRT; RNMX
UniProt ID: (Human) Q5JQ67, (Mouse) Q9WV02, (Rat) Q4V898
Entrez Gene ID: (Human) 27316, (Mouse) 19655, (Rat) 302855
regulation of alternative mRNA splicing, via spliceosome
osteoblast differentiation
transcription, DNA-templated
transcription from RNA polymerase II promoter
mRNA splice site selection
mRNA processing
membrane protein ectodomain proteolysis
RNA splicing
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cellular response to interleukin-1
mRNA splicing, via spliceosome
gene expression
negative regulation of mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome
protein homooligomerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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