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Invitrogen
RBMXL2 Recombinant Rabbit Monoclonal Antibody (JE64-33)
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FIGURE: 1 / 5
RBMXL2 Antibody (MA5-44704) in ICC/IF
Immunocytochemistry analysis of hnRNP G-T in HeLa cells. Cells were fixed in 4% paraformaldehyde for 10 minutes at 37 &(8)451;, permeabilized with 0.05% Triton X-100 in PBS for 20 minutes, and then blocked with 2% negative goat serum for 30 minutes at room temperature. Samples were incubated in hnRNP G-T Monoclonal antibody (Product # MA5-44704) using a dilution of 1:200 in 2% negative goat serum overnight at 4 &(8)451; followed by Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) secondary antibody at a dilution of 1:1,000. Nuclear DNA was labe... View More
Product Details
MA5-44704
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE64-33
Immunogen
Recombinant protein within human hnRNP G-T aa 151-350/392.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2931162
Target Information
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heterogeneous nuclear ribonucleoprotein G T; hnRNP G-T; RNA binding motif protein, X-linked-like 2; RNA-binding motif protein, X-linked-like-2; testes specific heterogenous nuclear ribonucleoprotein G T; testes-specific heterogenous nuclear ribonucleoprotein G-T; Testis-specific heterogeneous nuclear ribonucleoprotein G-T
Gene Aliases: 1700012H05Rik; HNRNPG-T; HNRNPGT; HNRPGT; RBMXL2
UniProt ID: (Human) O75526
Entrez Gene ID: (Rat) 103690209, (Human) 27288, (Mouse) 76572
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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