Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
RBP3 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
RBP3 Antibody (PA5-92951) in WB
Western blot analysis of RBP3 in extracts of various cell lines. Samples were incubated with RBP3 Polyclonal antibody (Product # PA5-92951) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-92951
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-320 of human RBP3 (NP_0028911)
Conjugate
Form
Liquid
Concentration
1.97 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806558
Product Specific Information
Immunogen sequence: GPTHLFQPSL VLDMAKVLLD NYCFPENLLG MQEAIQQAIK SHEILSISDP QTLASVLTAG VQSSLNDPRL VISYEPSTPE PPPQVPALTS LSEEELLAWL QRGLRHEVLE GNVGYLRVDS VPGQEVLSMM GEFLVAHVWG NLMGTSALVL DLRHCTGGQV SGIPYIISYL HPGNTILHVD TIYNRPSNTT TEIWTLPQVL GERYGADKDV VVLTSSQTRG VAEDIAHILK QMRRAIVVGE RTGGGALDLR KLRIGESDFF FTVPVSRSLG PLGGGSQTWE GSGVLPCVGT PAEQALEKAL AIL; Positive Samples: Mouse lung, Mouse eye, Rat eye; Cellular Location: extracellular matrix, extracellular space, interphotoreceptor matrix
Target Information
Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: interphotoreceptor retinoid binding protein; Interphotoreceptor retinoid-binding protein; interphotoreceptor retinol- binding protein; interstitial retinol binding protein 3; Interstitial retinol-binding protein; interstitial retinol-binding protein 3; IRBP; retinol binding protein 3, interstitial; Retinol-binding protein 3
Gene Aliases: D10S64; D10S65; D10S66; IRBP; Rbp-3; RBP3; RBPI; RP66
UniProt ID: (Human) P10745, (Mouse) P49194
Entrez Gene ID: (Human) 5949, (Rat) 24711, (Mouse) 19661
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support