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Invitrogen
RBP4 Polyclonal Antibody
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Product Details
PA5-29173
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RBP4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546649
Product Specific Information
Recommended positive controls: HepG2.
Predicted reactivity: Mouse (86%), Rat (86%), Cat (94%), Pig (92%), Rabbit (91%), Chimpanzee (100%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial
Gene Aliases: MCOPCB10; PRO2222; RBP4; RDCCAS
UniProt ID: (Human) P02753
Entrez Gene ID: (Human) 5950
retinoid metabolic process
eye development
gluconeogenesis
heart development
visual perception
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
retinol transport
retinol metabolic process
glucose homeostasis
response to ethanol
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
positive regulation of immunoglobulin secretion
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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