Invitrogen

RBPMS Polyclonal Antibody

4 Published Figures

5 References

View all (40) RBPMS antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (11)
Published Figures (4)

RBPMS Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 15

RBPMS Antibody (PA5-31231) in ICC/IF

Immunocytochemistry-Immunofluorescence analysis of RBPMS was performed in A549 cells fixed in 4% paraformaldehyde at RT for 15 min. Green: RBPMS Polyclonal Antibody (Product # PA5-31231) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.

RBPMS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RBPMS Antibody in Immunohistochemistry (IHC)

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Product Details

PA5-31231

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

Immunocytochemistry (ICC/IF)

1:100-1:1,000

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human RBPMS. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.55 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2548705

Product Specific Information

Recommended positive controls: A549, mouse heart.

Predicted reactivity: Mouse (99%), Rat (99%), Bovine (98%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM domain consists of two short stretches of conserved sequence called RNP1 and RNP2, as well as a few highly conserved hydrophobic residues. The protein encoded by this gene has a single, putative RRM domain in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The RBPMS^{CreERT2-tdTomato} mouse line for studying retinal and vascular relevant diseases.

iScience

Li G,Luo Y,Zhang Q,Chen W,Lai K,Liu Y,Zheng Y

Published figure using RBPMS polyclonal antibody (Product # PA5-31231) in Western Blot

Fri Nov 17 00:00:00 UTC 2023

Overexpressing NeuroD1 reprograms Müller cells into various types of retinal neurons.

Neural regeneration research

Xu D,Zhong LT,Cheng HY,Wang ZQ,Chen XM,Feng AY,Chen WY,Chen G,Xu Y

PA5-31231 was used in Immunohistochemistry to indicate that Müller cells in adult mice are highly plastic and can be reprogrammed into various subtypes of retinal neurons.

Mon May 01 00:00:00 UTC 2023

Genetic inhibition of collapsin response mediator protein-2 phosphorylation ameliorates retinal ganglion cell death in normal-tension glaucoma models.

Genes to cells : devoted to molecular & cellular mechanisms

Brahma MM,Takahashi K,Namekata K,Harada T,Goshima Y,Ohshima T

PA5-31231 was used in Immunocytochemistry, Immunohistochemistry - Free Floating, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to examine the phosphorylation of collapsin response mediator protein-2 (CRMP2), a protein that is abundantly expressed in neurons and involved in their development.

Mon Aug 01 00:00:00 UTC 2022

Genetic inhibition of collapsin response mediator protein-2 phosphorylation ameliorates retinal ganglion cell death in normal-tension glaucoma models.

Genes to cells : devoted to molecular & cellular mechanisms

Brahma MM,Takahashi K,Namekata K,Harada T,Goshima Y,Ohshima T

Mon Aug 01 00:00:00 UTC 2022

Echium amoenum L. Ethanol Extract Protects Retinal Ganglion Cell after Glutamate and Optic Nerve Crush Injury.

Disease markers

Li H,Behnammanesh G,Wu Z,Rong R,You M,Majid ASA,Ji D

PA5-31231 was used in Immunocytochemistry, Immunohistochemistry - Free Floating, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot to show that the ethanol extract of E. amoenum L. prevented the glutamate-induced decrease in cell viability and increase in cell death in R28 cells and suppressed the overproduction of ROS induced by glutamate.

Wed Oct 05 00:00:00 UTC 2022

Echium amoenum L. Ethanol Extract Protects Retinal Ganglion Cell after Glutamate and Optic Nerve Crush Injury.

Disease markers

Li H,Behnammanesh G,Wu Z,Rong R,You M,Majid ASA,Ji D

Wed Oct 05 00:00:00 UTC 2022

Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury.

Scientific reports

Kondo S,Takahashi K,Kinoshita Y,Nagai J,Wakatsuki S,Araki T,Goshima Y,Ohshima T

PA5-31231 was used in Immunocytochemistry-immunoflourescence to show axonal regeneration after optic nerve injury can be promoted by inhibiting serine 522 phosphorylation of collapsin response mediator protein 2.

Fri May 10 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: Heart and RRM expressed sequence; HEart, RRM Expressed Sequence; Hermes; RBP-MS; RNA binding protein gene with multiple splicing; RNA-binding protein gene with multiple splicing; RNA-binding protein with multiple splicing; RNA-binding protein with multiple splicing (RBP-MS)

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Gene Aliases: 2010300K22Rik; 2700019M19Rik; AU017537; HERMES; RBP-MS; RBPMS; RGD1561067

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UniProt ID: (Human) Q93062, (Mouse) Q9WVB0, (Rat) A0A8I6G705

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Entrez Gene ID: (Human) 11030, (Mouse) 19663, (Rat) 498642

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Function(s)

nucleotide binding transcription coactivator activity RNA binding protein binding poly(A) binding snRNA binding protein homodimerization activity poly(A) RNA binding nucleic acid binding

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated positive regulation of pathway-restricted SMAD protein phosphorylation positive regulation of SMAD protein import into nucleus regulation of nucleic acid-templated transcription mRNA splicing, via spliceosome RNA processing response to oxidative stress

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RBPMS Polyclonal Antibody

RBPMS Antibody (PA5-31231) in ICC/IF

Product Details

PA5-31231

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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