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RCBTB1 Antibody (PA5-99183) in ICC/IF
Immunofluorescent analysis of RCBTB1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with RCBTB1 polyclonal antibody (Product # PA5-99183) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-99183
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RCBTB1(Accession Q8NDN9), corresponding to amino acid residues W257-V307.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818116
Product Specific Information
Antibody detects endogenous levels of total RCBTB1.
Target Information
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; GDP/GTP exchange factor (GEF)-like protein; RCC1 and BTB domain-containing protein 1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1; RP11-185C18.1
Gene Aliases: 5430409I18Rik; AW111883; CLLD7; CLLL7; E4.5; GLP; RCBTB1
UniProt ID: (Human) Q8NDN9, (Mouse) Q6NXM2
Entrez Gene ID: (Human) 55213, (Mouse) 71330
Performance Guarantee
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