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Invitrogen
RCCD1 Polyclonal Antibody
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Product Details
PA5-58881
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RCCD1. Recombinant protein control fragment (Product #RP-98163).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646425
Product Specific Information
Immunogen sequence: ELEPRLLEAL QGLVMAEVAA GGWHSVCVSE TGDIYIWGWN ESGQLALPTR NLAEDGETVA REATELNEDG SQVKRTGG
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 77%.
Target Information
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860). Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation (PubMed:24981860). Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 (PubMed:28455245).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RCC1 domain-containing protein 1
Gene Aliases: RCCD1
UniProt ID: (Human) A6NED2
Entrez Gene ID: (Human) 91433
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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