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Immunogen sequence: LGKIVDRIDN DGDGFVTTEE LKTWIKRVQK RYIFDNVAKV WKDYDRDKDD KISWEEYKQA
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis secretory protein Li 84; FLJ37041; proliferation-inducing gene 20; reticulocalbin 1, EF-hand calcium binding domain; Reticulocalbin-1
Gene Aliases: HEL-S-84; PIG20; Rca1; RCAL; RCN; RCN1
UniProt ID: (Human) Q15293, (Mouse) Q05186
Entrez Gene ID: (Human) 5954, (Mouse) 19672
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