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Invitrogen
RCOR1 Polyclonal Antibody
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FIGURE: 1 / 3
RCOR1 Antibody (PA5-88800) in WB
Western blot analysis of RCOR1 in extracts of various cell lines. Samples were incubated with RCOR1 Polyclonal antibody (Product # PA5-88800) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-88800
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 256-485 of human CoREST/CoREST/RCOR1 (NP_0559712)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805141
Product Specific Information
Immunogen sequence: EREESEDELE EANGNNPIDI EVDQNKESKK EVPPTETVPQ VKKEKHSTQA KNRAKRKPPK GMFLSQEDVE AVSANATAAT TVLRQLDMEL VSVKRQIQNI KQTNSALKEK LDGGIEPYRL PEVIQKCNAR WTTEEQLLAV QAIRKYGRDF QAISDVIGNK SVVQVKNFFV NYRRRFNIDE VLQEWEAEHG KEETNGPSNQ KPVKSPDNSI KMPEEEDEAP VLDVRYASAS; Positive Samples: HeLa, Jurkat, Mouse testis, Mouse brain; Cellular Location: Nucleus
Target Information
RCOR1 is a functional corepressor required for regulation of neural-specific gene expression. The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression. The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein CoREST; REST corepressor 1
Gene Aliases: 5730409O11; 6720480E22Rik; AU042633; COREST; D12Wsu95e; KIAA0071; mKIAA0071; RCOR; RCOR1; Rocr1
UniProt ID: (Human) Q9UKL0, (Mouse) Q8CFE3
Entrez Gene ID: (Human) 23186, (Mouse) 217864
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
transcription regulatory region DNA binding
DNA binding
chromatin binding
enzyme binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
blood coagulation
viral process
negative regulation of transcription, DNA-templated
histone H4 deacetylation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
chromatin modification
erythrocyte differentiation
positive regulation of megakaryocyte differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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