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Invitrogen
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Recommended positive controls: A549, HeLa, Jurkat, NT2D1.
Predicted reactivity: Mouse (89%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 11-cis RDH; 11-cis retinol dehydrogenase; 11-cis RoDH; 9-cis retinol dehydrogenase; 9-cis-retinol specific dehydrogenase; 9cRDH; FLJ39337; FLJ97089; retinol dehydrogenase 1; Retinol dehydrogenase 5; retinol dehydrogenase 5 (11-cis and 9-cis); retinol dehydrogenase 5 (11-cis/9-cis); Short chain dehydrogenase/reductase family 9C member 5; short chain dehydrogenase/reductase family 9C, member 5
Gene Aliases: 9cRDH; HSD17B9; RDH1; RDH5; SDR9C5
UniProt ID: (Human) Q92781
Entrez Gene ID: (Human) 5959
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