Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Proteintech
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This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human REC8. This antibody can recognize the monomeric, non-phosphorylated form (63-70 kDa) of REC8 and other forms(80-100 kDa) which represent either post translationally modified forms or alternative transcript products.
Immunogen sequence: VLPPEAITI LEAEPIRMLE IEGERELPEV SRRELDLLIA EEEEAILLEI PRLPPPAPAE VEGIGEALGP EELRLTGWEP GALLMEVTPP EELRLPAPPS PERRPPVPPP PRRRRRRRLL FWDKETQISP EKFQEQLQTR AHCWECPMVQ PPERTIRGPA ELFRTPTLSG WLPPELLGLW THCAQPPPKA LRRELPEEAA AEEERRKIEV PSEIEVPREA LEPSVPLMVS LEISLEAAEE EKSRISLIPP EERWAWPEVE APEAPALPVV PELPEVPMEM PLVLPPELEL LSLEAVHRAV ALELQANREP DFSSLVSPLS PRRMAARVFY LLLVLSAQQI LHVKQEKPYG RLLIQPGPRF H (188-548 aa encoded by BC010887)
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cohesin Rec8p; cohesion rec8p; human homolog of rad21, S. pombe; kleisin-alpha; meiotic cohesion Rec8; meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family; Meiotic recombination protein REC8 homolog; meiotic recombination protein REC8-like 1; REC8 homolog; REC8-like 1; recombination and sister chromatid cohesion protein homolog
Gene Aliases: HR21spB; Mei8; mrec; REC8; REC8L1; Rec8p
UniProt ID: (Human) O95072, (Mouse) Q8C5S7
Entrez Gene ID: (Human) 9985, (Mouse) 56739
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