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Product Details
PA5-75608
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human RECQ4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719336
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent DNA helicase Q4; DNA 3'-5' helicase RecQ4; DNA helicase, RecQ-like type 4; DNA helicase, RecQ-like, type 4; RecQ helicase protein-like 4; RecQ helicase-like 4; RecQ protein-like 4; RecQ4; RTS
Gene Aliases: RECQ4; RECQL4
UniProt ID: (Human) O94761, (Mouse) Q75NR7
Entrez Gene ID: (Human) 9401, (Rat) 300057, (Mouse) 79456
bubble DNA binding
protein binding
ATP binding
four-way junction helicase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
molecular_function
nucleic acid binding
ATP-dependent helicase activity
zinc ion binding
nucleotide binding
helicase activity
hydrolase activity
metal ion binding
DNA strand renaturation
DNA replication
DNA repair
base-excision repair
double-strand break repair
DNA recombination
multicellular organism development
DNA duplex unwinding
skeletal system development
biological_process
positive regulation of cell proliferation
pigmentation
negative regulation of sister chromatid cohesion
skeletal system morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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