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Immunogen sequence: MTRKQRESVL QKIRAAQVHV LMLTPEALVG AGGLPPAAQL PPVAFACIDE AHCLSQWSHN FRPCYLRVCK VLRERMGVHC FLGLTATATR RTASDVAQHL AVAEEPDLHG PAPVPTNLHL SVSMDRDTDQ ALLTLLQGKR FQNLDSIIIY CNRREDTERI AALLRTCLHA AWVPGSGGRA PKTTAEAYHA GMCSRERRRV QRAFMQGQLR VVVATVAFGM GLDRPDVRAV LHLGLPPSFE SYVQAVGRAG RDGQPAHCHL FLQPQGEDLR ELRRHVHADS TDFLAVKRLV QRVFPACTCT CTRPPSEQEG AVGGERPVPK YPPQEAEQLS HQAAPGPRRV CMGHERALPI QLTVQALDMP EEAIETLLCY LELHPHHWLE LLATTYTHCR LNCPGGPAQL QALAHRCPPL AVCLAQQLPE DPGQGSSSVE FDMVKLVDSM GWELASVRRA LCQLQWDHEP RTGVRRGTGV LVEFSELAFH LRSPGDLTAE EKDQICDFLY GRVQARERQA LARLRRTFQA FHSVAFPSCG PCLEQQDEER STRLKDLLGR YFEEEEGQEP GGMEDAQGPE PGQARLQDWE DQVRCDIRQF LSLRPEEKFS SRAVARIFHG IGSPCYPAQV YGQDRRFWRK YLHLSFHALV GLATEELLQV AR
The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent DNA helicase Q4; DNA 3'-5' helicase RecQ4; DNA helicase, RecQ-like type 4; DNA helicase, RecQ-like, type 4; RecQ helicase-like 4; RecQ protein-like 4; RecQ4; RTS
Gene Aliases: RECQ4; RECQL4
UniProt ID: (Human) O94761
Entrez Gene ID: (Human) 9401
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