Proteintech

REEP1 Polyclonal Antibody

REEP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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REEP1 Antibody (17988-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using (Product # 17988-1-AP) (REEP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

REEP1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17988-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

REEP1 Fusion Protein Ag12418 (70-201 aa encoded by BC064846)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IAFVAWLLS PYTKGSSLLY RKFVHPTLSS KEKEIDDCLV QAKDRSYDAL VHFGKRGLNV AATAAVMAAS KGQGALSERL RSFSMQDLTT IRGDGAPAPS GPPPPGSGRA SGKHGQPKMS RSASESASSS GTA (70-201 aa encoded by BC064846)

Target Information

REEP1 belongs to the DP1 family and may enhance the cell surface expression of odorant receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.

Nature

Foronda H,Fu Y,Covarrubias-Pinto A,Bocker HT,González A,Seemann E,Franzka P,Bock A,Bhaskara RM,Liebmann L,Hoffmann ME,Katona I,Koch N,Weis J,Kurth I,Gleeson JG,Reggiori F,Hummer G,Kessels MM,Qualmann B,Mari M,Dikić I,Hübner CA

Thu Jun 01 00:00:00 UTC 2023

Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.

Human molecular genetics

Zhu PP,Hung HF,Batchenkova N,Nixon-Abell J,Henderson J,Zheng P,Renvoisé B,Pang S,Xu CS,Saalfeld S,Funke J,Xie Y,Svara F,Hess HF,Blackstone C

Tue Aug 23 00:00:00 UTC 2022

Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy.

Neurobiology of disease

Behrendt L,Hoischen C,Kaether C

Thu Jul 01 00:00:00 UTC 2021

DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.

Autophagy

Tian X,Zheng P,Zhou C,Wang X,Ma H,Ma W,Zhou X,Teng J,Chen J

Fri May 01 00:00:00 UTC 2020

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 UTC 2018

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 UTC 2018

DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.

Cell research

Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J

Wed Aug 01 00:00:00 UTC 2018

Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.

Molecular psychiatry

Sharoar MG,Shi Q,Ge Y,He W,Hu X,Perry G,Zhu X,Yan R

Thu Sep 01 00:00:00 UTC 2016

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.

Human molecular genetics

Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C

Thu Dec 01 00:00:00 UTC 2016

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.

Human molecular genetics

Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C

Thu Dec 01 00:00:00 UTC 2016

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.

Human molecular genetics

Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C

Thu Dec 01 00:00:00 UTC 2016

Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.

Human molecular genetics

Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C

Thu Dec 01 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: rcG_56072; Receptor expression-enhancing protein 1; Spastic paraplegia 31 protein

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Gene Aliases: C2orf23; D6Ertd253e; HMN5B; REEP1; RGD1305230; SPG31; Yip2a

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UniProt ID: (Human) Q9H902, (Mouse) Q8BGH4

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Entrez Gene ID: (Human) 65055, (Mouse) 52250, (Rat) 362384

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Function(s)

protein binding microtubule binding olfactory receptor binding

Process(es)

regulation of intracellular transport protein insertion into membrane endoplasmic reticulum tubular network organization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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REEP1 Polyclonal Antibody

REEP1 Antibody (17988-1-AP) in IHC (P)

Product Details

17988-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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