Product References
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.
Nature
González A,Covarrubias-Pinto A,Bhaskara RM,Glogger M,Kuncha SK,Xavier A,Seemann E,Misra M,Hoffmann ME,Bräuning B,Balakrishnan A,Qualmann B,Dötsch V,Schulman BA,Kessels MM,Hübner CA,Heilemann M,Hummer G,Dikić I
Thu Jun 01 00:00:00 UTC 2023
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.
Nature
González A,Covarrubias-Pinto A,Bhaskara RM,Glogger M,Kuncha SK,Xavier A,Seemann E,Misra M,Hoffmann ME,Bräuning B,Balakrishnan A,Qualmann B,Dötsch V,Schulman BA,Kessels MM,Hübner CA,Heilemann M,Hummer G,Dikić I
Thu Jun 01 00:00:00 UTC 2023
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Nature
Foronda H,Fu Y,Covarrubias-Pinto A,Bocker HT,González A,Seemann E,Franzka P,Bock A,Bhaskara RM,Liebmann L,Hoffmann ME,Katona I,Koch N,Weis J,Kurth I,Gleeson JG,Reggiori F,Hummer G,Kessels MM,Qualmann B,Mari M,Dikić I,Hübner CA
Thu Jun 01 00:00:00 UTC 2023
Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication.
Cell reports
Tan X,Cai K,Li J,Yuan Z,Chen R,Xiao H,Xu C,Hu B,Qin Y,Ding B
Tue Apr 25 00:00:00 UTC 2023
Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency.
Research square
Le W,Wang P,Al-Nusaif M,Zhang J,Yang H,Yang Y,Kim K,Li S,Liu C,Cai H
Thu May 18 00:00:00 UTC 2023
Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting.
Cells
Tirincsi A,O'Keefe S,Nguyen D,Sicking M,Dudek J,Förster F,Jung M,Hadzibeganovic D,Helms V,High S,Zimmermann R,Lang S
Mon Sep 19 00:00:00 UTC 2022
Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.
Human molecular genetics
Zhu PP,Hung HF,Batchenkova N,Nixon-Abell J,Henderson J,Zheng P,Renvoisé B,Pang S,Xu CS,Saalfeld S,Funke J,Xie Y,Svara F,Hess HF,Blackstone C
Tue Aug 23 00:00:00 UTC 2022
ER proteins decipher the tubulin code to regulate organelle distribution.
Nature
Zheng P,Obara CJ,Szczesna E,Nixon-Abell J,Mahalingan KK,Roll-Mecak A,Lippincott-Schwartz J,Blackstone C
Sat Jan 01 00:00:00 UTC 2022
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia.
Acta neuropathologica communications
Byrne DJ,Garcia-Pardo ME,Cole NB,Batnasan B,Heneghan S,Sohail A,Blackstone C,O'Sullivan NC
Mon Mar 28 00:00:00 UTC 2022
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia.
Acta neuropathologica communications
Byrne DJ,Garcia-Pardo ME,Cole NB,Batnasan B,Heneghan S,Sohail A,Blackstone C,O'Sullivan NC
Mon Mar 28 00:00:00 UTC 2022
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia.
Acta neuropathologica communications
Byrne DJ,Garcia-Pardo ME,Cole NB,Batnasan B,Heneghan S,Sohail A,Blackstone C,O'Sullivan NC
Mon Mar 28 00:00:00 UTC 2022
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Autophagy
Zielke S,Kardo S,Zein L,Mari M,Covarrubias-Pinto A,Kinzler MN,Meyer N,Stolz A,Fulda S,Reggiori F,Kögel D,van Wijk S
Wed Sep 01 00:00:00 UTC 2021
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Autophagy
Zielke S,Kardo S,Zein L,Mari M,Covarrubias-Pinto A,Kinzler MN,Meyer N,Stolz A,Fulda S,Reggiori F,Kögel D,van Wijk S
Wed Sep 01 00:00:00 UTC 2021
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
The Journal of cell biology
Chen F,Yan B,Ren J,Lyu R,Wu Y,Guo Y,Li D,Zhang H,Hu J
Mon May 03 00:00:00 UTC 2021
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins.
The Journal of cell biology
Chen F,Yan B,Ren J,Lyu R,Wu Y,Guo Y,Li D,Zhang H,Hu J
Mon May 03 00:00:00 UTC 2021
A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells.
BMC bioinformatics
Garcia-Pardo ME,Simpson JC,O'Sullivan NC
Wed Sep 08 00:00:00 UTC 2021
A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes.
Nature chemical biology
Cheng YS,Zhang T,Ma X,Pratuangtham S,Zhang GC,Ondrus AA,Mafi A,Lomenick B,Jones JJ,Ondrus AE
Wed Dec 01 00:00:00 UTC 2021
Mechanism of membrane-curvature generation by ER-tubule shaping proteins.
Nature communications
Wang N,Clark LD,Gao Y,Kozlov MM,Shemesh T,Rapoport TA
Mon Jan 25 00:00:00 UTC 2021
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Cell metabolism
Wang X,Wang H,Xu B,Huang D,Nie C,Pu L,Zajac GJM,Yan H,Zhao J,Shi F,Emmer BT,Lu J,Wang R,Dong X,Dai J,Zhou W,Wang C,Gao G,Wang Y,Willer C,Lu X,Zhu Y,Chen XW
Tue Feb 02 00:00:00 UTC 2021
A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.
Cell
Liang JR,Lingeman E,Luong T,Ahmed S,Muhar M,Nguyen T,Olzmann JA,Corn JE
Thu Mar 19 00:00:00 UTC 2020
Functional culture and in vitro genetic and small-molecule manipulation of adult mouse cardiomyocytes.
Communications biology
Callaghan NI,Lee SH,Hadipour-Lakmehsari S,Lee XA,Ahsan Siraj M,Driouchi A,Yip CM,Husain M,Simmons CA,Gramolini AO
Mon May 11 00:00:00 UTC 2020
Functional culture and in vitro genetic and small-molecule manipulation of adult mouse cardiomyocytes.
Communications biology
Callaghan NI,Lee SH,Hadipour-Lakmehsari S,Lee XA,Ahsan Siraj M,Driouchi A,Yip CM,Husain M,Simmons CA,Gramolini AO
Mon May 11 00:00:00 UTC 2020
Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190.
Cell chemical biology
Dickson P,Abegg D,Vinogradova E,Takaya J,An H,Simanski S,Cravatt BF,Adibekian A,Kodadek T
Thu Nov 19 00:00:00 UTC 2020
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
Scientific reports
Yamanaka T,Nishiyama R,Shimogori T,Nukina N
Wed May 06 00:00:00 UTC 2020
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
Scientific reports
Yamanaka T,Nishiyama R,Shimogori T,Nukina N
Wed May 06 00:00:00 UTC 2020
DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.
Autophagy
Tian X,Zheng P,Zhou C,Wang X,Ma H,Ma W,Zhou X,Teng J,Chen J
Fri May 01 00:00:00 UTC 2020
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
Nature communications
Lee SH,Hadipour-Lakmehsari S,Murthy HR,Gibb N,Miyake T,Teng ACT,Cosme J,Yu JC,Moon M,Lim S,Wong V,Liu P,Billia F,Fernandez-Gonzalez R,Stagljar I,Sharma P,Kislinger T,Scott IC,Gramolini AO
Wed Feb 19 00:00:00 UTC 2020
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
Nature communications
Lee SH,Hadipour-Lakmehsari S,Murthy HR,Gibb N,Miyake T,Teng ACT,Cosme J,Yu JC,Moon M,Lim S,Wong V,Liu P,Billia F,Fernandez-Gonzalez R,Stagljar I,Sharma P,Kislinger T,Scott IC,Gramolini AO
Wed Feb 19 00:00:00 UTC 2020
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
Nature communications
Lee SH,Hadipour-Lakmehsari S,Murthy HR,Gibb N,Miyake T,Teng ACT,Cosme J,Yu JC,Moon M,Lim S,Wong V,Liu P,Billia F,Fernandez-Gonzalez R,Stagljar I,Sharma P,Kislinger T,Scott IC,Gramolini AO
Wed Feb 19 00:00:00 UTC 2020
REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.
Nature communications
Lee SH,Hadipour-Lakmehsari S,Murthy HR,Gibb N,Miyake T,Teng ACT,Cosme J,Yu JC,Moon M,Lim S,Wong V,Liu P,Billia F,Fernandez-Gonzalez R,Stagljar I,Sharma P,Kislinger T,Scott IC,Gramolini AO
Wed Feb 19 00:00:00 UTC 2020
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Molecular cell
An H,Ordureau A,Paulo JA,Shoemaker CJ,Denic V,Harper JW
Thu Jun 06 00:00:00 UTC 2019
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Current biology : CB
Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J
Mon Mar 04 00:00:00 UTC 2019
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Current biology : CB
Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J
Mon Mar 04 00:00:00 UTC 2019
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Current biology : CB
Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J
Mon Mar 04 00:00:00 UTC 2019
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Current biology : CB
Chen Q,Xiao Y,Chai P,Zheng P,Teng J,Chen J
Mon Mar 04 00:00:00 UTC 2019
REEP3 and REEP4 determine the tubular morphology of the endoplasmic reticulum during mitosis.
Molecular biology of the cell
Kumar D,Golchoubian B,Belevich I,Jokitalo E,Schlaitz AL
Sat Jun 01 00:00:00 UTC 2019
Sequential formation of different layers of dystrophic neurites in Alzheimer's brains.
Molecular psychiatry
Sharoar MG,Hu X,Ma XM,Zhu X,Yan R
Sun Sep 01 00:00:00 UTC 2019
Proteomic analysis of murine bone marrow derived dendritic cells in response to peste des petits ruminants virus.
Research in veterinary science
Li L,Wu J,Cao X,Zhou J,Yin S,Yang S,Feng Q,Du P,Liu Y,Shang Y,Liu Y,Liu X
Thu Aug 01 00:00:00 UTC 2019
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Cell research
Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J
Wed Aug 01 00:00:00 UTC 2018
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Cell research
Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J
Wed Aug 01 00:00:00 UTC 2018
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Cell research
Zheng P,Chen Q,Tian X,Qian N,Chai P,Liu B,Hu J,Blackstone C,Zhu D,Teng J,Chen J
Wed Aug 01 00:00:00 UTC 2018
Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice.
The Journal of experimental medicine
Chiang ACA,Fowler SW,Savjani RR,Hilsenbeck SG,Wallace CE,Cirrito JR,Das P,Jankowsky JL
Mon May 07 00:00:00 UTC 2018
Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice.
The Journal of experimental medicine
Chiang ACA,Fowler SW,Savjani RR,Hilsenbeck SG,Wallace CE,Cirrito JR,Das P,Jankowsky JL
Mon May 07 00:00:00 UTC 2018
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Quantitative proteomics reveal proteins enriched in tubular endoplasmic reticulum of Saccharomyces cerevisiae.
eLife
Wang X,Li S,Wang H,Shui W,Hu J
Mon Mar 13 00:00:00 UTC 2017
Quantitative proteomics reveal proteins enriched in tubular endoplasmic reticulum of Saccharomyces cerevisiae.
eLife
Wang X,Li S,Wang H,Shui W,Hu J
Mon Mar 13 00:00:00 UTC 2017
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Molecular psychiatry
Sharoar MG,Shi Q,Ge Y,He W,Hu X,Perry G,Zhu X,Yan R
Thu Sep 01 00:00:00 UTC 2016
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Molecular psychiatry
Sharoar MG,Shi Q,Ge Y,He W,Hu X,Perry G,Zhu X,Yan R
Thu Sep 01 00:00:00 UTC 2016
Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants.
Traffic (Copenhagen, Denmark)
Spratley SJ,Hill CH,Viuff AH,Edgar JR,Skjødt K,Deane JE
Mon Aug 01 00:00:00 UTC 2016
Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.
Human molecular genetics
Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C
Thu Dec 01 00:00:00 UTC 2016
Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.
Human molecular genetics
Renvoisé B,Malone B,Falgairolle M,Munasinghe J,Stadler J,Sibilla C,Park SH,Blackstone C
Thu Dec 01 00:00:00 UTC 2016
A high-content screening microscopy approach to dissect the role of Rab proteins in Golgi-to-ER retrograde trafficking.
Journal of cell science
Galea G,Bexiga MG,Panarella A,O'Neill ED,Simpson JC
Wed Jul 01 00:00:00 UTC 2015
A high-content screening microscopy approach to dissect the role of Rab proteins in Golgi-to-ER retrograde trafficking.
Journal of cell science
Galea G,Bexiga MG,Panarella A,O'Neill ED,Simpson JC
Wed Jul 01 00:00:00 UTC 2015
ER network formation and membrane fusion by atlastin1/SPG3A disease variants.
Molecular biology of the cell
Ulengin I,Park JJ,Lee TH
Fri May 01 00:00:00 UTC 2015
ER network formation and membrane fusion by atlastin1/SPG3A disease variants.
Molecular biology of the cell
Ulengin I,Park JJ,Lee TH
Fri May 01 00:00:00 UTC 2015
Spastin binds to lipid droplets and affects lipid metabolism.
PLoS genetics
Papadopoulos C,Orso G,Mancuso G,Herholz M,Gumeni S,Tadepalle N,Jüngst C,Tzschichholz A,Schauss A,Höning S,Trifunovic A,Daga A,Rugarli EI
Wed Apr 01 00:00:00 UTC 2015
Spastin binds to lipid droplets and affects lipid metabolism.
PLoS genetics
Papadopoulos C,Orso G,Mancuso G,Herholz M,Gumeni S,Tadepalle N,Jüngst C,Tzschichholz A,Schauss A,Höning S,Trifunovic A,Daga A,Rugarli EI
Wed Apr 01 00:00:00 UTC 2015
Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A.
Human molecular genetics
Zhu PP,Denton KR,Pierson TM,Li XJ,Blackstone C
Sat Nov 01 00:00:00 UTC 2014
Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A.
Human molecular genetics
Zhu PP,Denton KR,Pierson TM,Li XJ,Blackstone C
Sat Nov 01 00:00:00 UTC 2014
Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Proceedings of the National Academy of Sciences of the United States of America
Chang J,Lee S,Blackstone C
Tue Sep 10 00:00:00 UTC 2013
Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Proceedings of the National Academy of Sciences of the United States of America
Chang J,Lee S,Blackstone C
Tue Sep 10 00:00:00 UTC 2013
Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Proceedings of the National Academy of Sciences of the United States of America
Chang J,Lee S,Blackstone C
Tue Sep 10 00:00:00 UTC 2013
Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Proceedings of the National Academy of Sciences of the United States of America
Chang J,Lee S,Blackstone C
Tue Sep 10 00:00:00 UTC 2013