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REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. REG1B may be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Protein Aliases: lithostathine 1 beta; Lithostathine-1-beta; Pancreatic stone protein 2; PSP-2; REG-1-beta; regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein); Regenerating islet-derived protein 1-beta; Regenerating protein I beta; secretory pancreatic stone protein 2
Gene Aliases: PSPS2; REG1B; REGH; REGI-BETA; REGL
UniProt ID: (Human) P48304
Entrez Gene ID: (Human) 5968
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