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Purity is > 95% by SDS-PAGE.
Reg IV is part of the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric and intestinal cell proliferation and differentiation. Reg IV is a 158-amino acid secretory protein implicated in cell regeneration and/or survival with a definite growth stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate and other types of cancer. Reg IV-positive tumor cells display different phenotypes including mucus-secreting, enterocyte-like, and undifferentiated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FNRA; Gastrointestinal secretory protein; GISPREG-4; ITGA5; Reg IV; REG-4; REG-like protein; regenerating gene type IV; regenerating islet-derived family, member 4; Regenerating islet-derived protein 4; Regenerating islet-derived protein IV
Gene Aliases: 2010002L15Rik; GISP; REG-IV; REG4; RELP
UniProt ID: (Human) Q9BYZ8, (Mouse) Q9D8G5, (Rat) Q68AX7
Entrez Gene ID: (Human) 83998, (Mouse) 67709, (Rat) 445583
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