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Immunogen sequence: DIIMRPSCAP GWFYHKSNCY GYFRKLRNWS DAELECQSYG NGAHLASILS LKEASTIAEY ISGYQRSQPI WIGLHDPQKR QQWQWIDGAM YLYRSWSGKS MGGNKHCAEM SSNNNFLTWS SNECNKRQHF LCKYRP; Positive Samples: Mouse stomach, Rat stomach
Reg IV is part of the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric and intestinal cell proliferation and differentiation. Reg IV is a 158-amino acid secretory protein implicated in cell regeneration and/or survival with a definite growth stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate and other types of cancer. Reg IV-positive tumor cells display different phenotypes including mucus-secreting, enterocyte-like, and undifferentiated.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FNRA; GISPREG-4; ITGA5; REG-4; Regenerating islet-derived protein 4
Gene Aliases: 2010002L15Rik; GISP; Reg4; RELP
UniProt ID: (Mouse) Q9D8G5, (Rat) Q68AX7
Entrez Gene ID: (Mouse) 67709, (Rat) 445583
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