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Invitrogen
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Immunogen sequence: LHGIFPYLYVP YDGYGQQPES YLSQMAFSID RALNVALGNP SSTAQHVFKV SLVSGMPFYG YHEKERHFMK IYLYNPTMVK RICE
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 95%.
Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA polymerase zeta catalytic subunit; Protein reversionless 3-like; Rev-3, yeast, homolog-like (polymerase, DNA, zeta); REV3-like; REV3-like, polymerase (DNA directed), zeta, catalytic subunit
Gene Aliases: POLZ; REV3; REV3L
UniProt ID: (Human) O60673
Entrez Gene ID: (Human) 5980
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