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Product Details
PA5-90722
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 26-237 of human REXO2 (NP_0563382)
Conjugate
Form
Liquid
Concentration
2.34 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806203
Product Specific Information
Immunogen sequence: VREGGAAMAA GESMAQRMVW VDLEMTGLDI EKDQIIEMAC LITDSDLNIL AEGPNLIIKQ PDELLDSMSD WCKEHHGKSG LTKAVKESTI TLQQAEYEFL SFVRQQTPPG LCPLAGNSVH EDKKFLDKYM PQFMKHLHYR IIDVSTVKEL CRRWYPEEYE FAPKKAASHR ALDDISESIK ELQFYRNNIF KKKIDEKKRK IIENGENEKT VS; Positive Samples: 293T, U-87MG, LO2, HT-29; Cellular Location: Cytoplasm, Mitochondrion intermembrane space, Mitochondrion matrix, Nucleus
Target Information
Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C11orf61; novel KRAB box domain containing protein; Oligoribonuclease, mitochondrial; reduced expression 2; REX2, RNA exonuclease 2 homolog; RNA exonuclease 2 homolog; Small fragment nuclease
Gene Aliases: 1810038D15Rik; AW107347; CGI-114; Gm13138; OTTMUSG00000010655; REX2; REXO2; RFN; SFN; SMFN
UniProt ID: (Human) Q9Y3B8, (Mouse) Q9D8S4, (Rat) Q5U1X1
Entrez Gene ID: (Human) 25996, (Mouse) 100043034, (Mouse) 104444, (Rat) 300689
3'-5'-exoribonuclease activity
nucleic acid binding
3'-5' exonuclease activity
transcription factor activity, sequence-specific DNA binding
nuclease activity
exonuclease activity
hydrolase activity
hydrolase activity, acting on ester bonds
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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