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Invitrogen
RFP2 Polyclonal Antibody
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Product Details
PA5-51377
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RFP2. Recombinant protein control fragment (Product #RP-94749).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646489
Product Specific Information
Immunogen sequence: LSRLDTLETS KRKSLQLLTK DSDKVKEFFE KLQHTLDQKK NEILSDFETM KLAVMQAYDP EINKLNTILQ EQRMAFNIAE AFKDVSEPIV FLQQMQEFRE KIKVIKETPL PPSNLPASPL MKNFDTSQWE DIKLVDVDKL SLP
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 97%.
Target Information
The protein encoded by the RFP2 gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. The gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell chronic lymphocytic leukemia tumor suppressor Leu5; CLL-associated RING finger; E3 ubiquitin-protein ligase TRIM13; Leukemia-associated protein 5; Putative tumor suppressor RFP2; Ret finger protein 2; RING finger protein 77; RING-type E3 ubiquitin transferase TRIM13; tripartite motif protein 13; tripartite motif-containing 13; Tripartite motif-containing protein 13
Gene Aliases: CAR; DLEU5; LEU5; RFP2; RNF77; TRIM13
UniProt ID: (Human) O60858
Entrez Gene ID: (Human) 10206
signal transduction
anatomical structure morphogenesis
response to gamma radiation
positive regulation of cell death
positive regulation of macroautophagy
ER-associated ubiquitin-dependent protein catabolic process
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
innate immune response
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
negative regulation of viral release from host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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