Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
RFTN1 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
24289-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RFTN1 Fusion Protein Ag17264 (29-374 aa encoded by BC100667)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ETKIDVSYE YRFLEFTTLS AAELPGSSAV RLASLRDLPA QLLELYQQGF SLAALHPFVQ PTHEREKTPL EHIFRAILIK KTDRSQKTDL HNEGYILELD CCSSLDHPTD QKLIPEFIKK IQEAASQGLK FVGVIPQYHS SVNSAGSSAP VSTANSTEDA RDAKNARGDH ASLENEKPGT GDVCSAPAGR NQSPEPSSGP RGEVPLAKQP SSPSGEGDGG ELSPQGVSKT LDGPESNPLE VHEEPLSGKM EIFTLFNKPK SHQKCRQYYP VTIPLHVSKN GQTVSGLDAN WLEHMSDHFR KGGMLVNAVF YLGIVNDSLH GLTDGVFIFE AVSTEDSKTI QGYDAIV (29-374 aa encoded by BC100667)
Target Information
Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), cell migration-inducing gene 2 protein, PIB10, PIG9 or MIG2, is a 578 amino acid cell membrane protein and lipid anchor that is essential for raft cell assembly and maintenance. A member of the raftlin family, Raftlin modulates B-cell antigen receptor-mediated signaling, TCR signals, and is involved in T cell-mediated immune responses. The gene encoding Raftlin maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell migration-inducing gene 2 protein; proliferation-inducing protein 10; proliferation-inducing protein 9; Raft-linking protein; Raftlin
Gene Aliases: KIAA0084; MIG2; PIB10; PIG9; RAFTLIN; RFTN1
UniProt ID: (Human) Q14699
Entrez Gene ID: (Human) 23180
membrane raft assembly
T cell antigen processing and presentation
protein transport into membrane raft
interleukin-17 production
dsRNA transport
toll-like receptor 3 signaling pathway
growth
response to exogenous dsRNA
T cell receptor signaling pathway
B cell receptor signaling pathway
protein localization to membrane raft
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support