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Product Details
17854-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RFTN2 Fusion Protein Ag12307 (3-501 aa encoded by BC111069)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CGLRKLEDP DDSSPGKIFS TLKRPQVETK TEFAYEYVLL DFTLQASSNP EVIKINSILD IVTKVENYYL KGYIVGAIHP VIQPVGQRKH LPASYLYRVV LLRLKLSPKN SAAPSGQRRP RLVIEECPLT SEAQTNDAAK ELIEKINVAA KRGMKFVGFI SQHYSPSKFC NGTNHDGDIE SMLHVRHGSD ENCRSWNEGT LSGQSSESGI EEELHHESGQ YQMEQNGSPT SSKSRKGEAS DNKLYTVFNA FDDDSTSWAY QEGILSMKVT RKGSVISTLD ADWLELTTFY YKQGLSLIDS FVFWETSKGE HLPKSLEGFF IYEEEGSGVP GSSRKGNDAI VVEQWTVIEG CEIKTDYGPL LHTLAEFGWL LTSVLPTPVL RHDSEGNLAT KQIVFLQRPV MWNSAAQTPD KKASRHIKGE DKNKATSRSI GLDTTSSQPA ESRHLPEECR LSPSRECWTK EGRLAQHNSF SGFSSSDNVL RELDDGQFDQ EDGVTQVTCM (3-501 aa encoded by BC111069)
Target Information
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Raft-linking protein 2; Raftlin-2
Gene Aliases: 2700010E02Rik; 3222401M22Rik; C2orf11; Raftlin-2; RFTN2
UniProt ID: (Human) Q52LD8, (Mouse) Q8CHX7
Entrez Gene ID: (Human) 130132, (Mouse) 74013
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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