Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Antibody detects endogenous levels of total RFTN2.
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Raft-linking protein 2; raftlin family member 2; Raftlin-2
Gene Aliases: 2700010E02Rik; 3222401M22Rik; C2orf11; Raftlin-2; RFTN2; RGD1307304
UniProt ID: (Human) Q52LD8, (Mouse) Q8CHX7
Entrez Gene ID: (Human) 130132, (Mouse) 74013, (Rat) 363231
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