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Invitrogen
RFTN2 Polyclonal Antibody
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FIGURE: 1 / 1
RFTN2 Antibody (PA5-116587) in WB
Western blot analysis of RFTN2 in extracts of various cell lines. Samples were incubated with RFTN2 Polyclonal antibody (Product # PA5-116587) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-116587
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 412-501 of human RFTN2 (NP_6532302)
Conjugate
Form
Liquid
Concentration
1.58 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901218
Product Specific Information
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: KKASRHIKGE DKNKATSRSI GLDTTSSQPA ESRHLPEECR LSPSRECWTK EGRLAQHNSF SGFSSSDNVL RELDDGQFDQ EDGVTQVTCM
Target Information
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Raft-linking protein 2; raftlin family member 2; Raftlin-2
Gene Aliases: 2700010E02Rik; 3222401M22Rik; Rftn2; RGD1307304
UniProt ID: (Mouse) Q8CHX7
Entrez Gene ID: (Mouse) 74013, (Rat) 363231
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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