Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: NVAAKRGMKF VGFISQHYSP SKFCNGTNHD GDIESMLHVR HGSDENCRSW NEGTLSGQSS ESGIEEELHH ESGQYQMEQN GSPTSSKSRK GE
Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 58%.
Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Raft-linking protein 2; Raftlin-2
Gene Aliases: C2orf11; Raftlin-2; RFTN2
UniProt ID: (Human) Q52LD8
Entrez Gene ID: (Human) 130132
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