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Proteintech
RFX3 Polyclonal Antibody
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Product Details
14784-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RFX3 Fusion Protein Ag6413 (1-413 aa encoded by BC067778)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQTSETGSD TGSTVTLQTS VASQAAVPTQ VVQQVPVQQQ VQQVQTVQQV QHVYPAQVQY VEGSDTVYTN GAIRTTTYPY TETQMYSQNT GGNYFDTQGS SAQVTTVVSS HSMVGTGGIQ MGVTGGQLIS SSGGTYLIGN SMENSGHSVT HTTRASPATI EMAIETLQKS DGLSTHRSSL LNSHLQWLLD NYETAEGVSL PRSTLYNHYL RHCQEHKLDP VNAASFGKLI RSIFMGLRTR RLGTRGNSKY HYYGIRVKPD SPLNRLQEDM QYMAMRQQPM QQKQRYKPMQ KVDGVADGFT GSGQQTGTSV GQTVIAQSQH HQQFLDASRA LPEFGEVEIS SLPDGTTFED IKSLQSLYRE HCEAILDVVV NLQFSLIEKL WQTFWRYSPS TPTDGTTITE SRSESTSFPI HFHG (1-413 aa encoded by BC067778)
Target Information
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bA32F11.1; DNA binding protein RFX3; Regulatory factor X 3; regulatory factor X, 3 (influences HLA class II expression); Transcription factor RFX3
Gene Aliases: C230093O12Rik; MRFX3; RFX3
UniProt ID: (Human) P48380, (Mouse) P48381
Entrez Gene ID: (Human) 5991, (Mouse) 19726, (Rat) 361746
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription regulatory region DNA binding
sequence-specific DNA binding
type B pancreatic cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
endocrine pancreas development
cilium assembly
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell maturation
regulation of insulin secretion
cilium-dependent cell motility
epithelial cilium movement involved in determination of left/right asymmetry
type B pancreatic cell maturation
positive regulation of type B pancreatic cell development
multicellular organism development
determination of left/right symmetry
cell differentiation
regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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