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Invitrogen
RFX4 Polyclonal Antibody
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Product Details
PA5-107240
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N terminal region of human RFX4
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.4, with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2817956
Product Specific Information
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Target Information
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Regulatory factor X 4; regulatory factor X, 4 (influences HLA class II expression); Testis development protein NYD-SP10; Transcription factor RFX4; winged-helix transcription factor RFX4
Gene Aliases: NYD-SP10; RFX4
UniProt ID: (Human) Q33E94
Entrez Gene ID: (Human) 5992
transcription from RNA polymerase II promoter
dorsal spinal cord development
telencephalon development
cerebellar cortex morphogenesis
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
midbrain development
cilium assembly
positive regulation of transcription from RNA polymerase II promoter
regulation of protein processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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