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Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.
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Protein Aliases: DRAGON; DRG11-responsive axonal guidance and outgrowth of neurite; Repulsive guidance molecule B; repulsive guidance molecule family member B; RGM domain family member B; RGM domain family, member B
Gene Aliases: 1110059F19Rik; DRAGON; RGMB
UniProt ID: (Human) Q6NW40, (Mouse) Q7TQ33
Entrez Gene ID: (Human) 285704, (Mouse) 68799, (Rat) 681433
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