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Product Details
OSR00248W-150UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from human RGS19 conjugated to blue carrier protein has been used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: RGS19.
Target Information
RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium/calmodulin-dependent protein kinase I; G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19
Gene Aliases: 2610042F04Rik; AI324841; AW547781; Camki; GAIP; GNAI3IP; RGS19; RGSGAIP
UniProt ID: (Human) P49795, (Mouse) Q9CX84, (Rat) O70521
Entrez Gene ID: (Human) 10287, (Mouse) 56470, (Rat) 59293
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
positive regulation of GTPase activity
biological_process
regulation of G-protein coupled receptor protein signaling pathway
regulation of transcription, DNA-templated
autophagy
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
cell death
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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