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RGS19 Antibody (PA5-104092) in WB
Western blot analysis of RGS19 in extracts from various samples. Samples were incubated with RGS19 polyclonal antibody (Product # PA5-104092). Lane 1: COS-7 cells (UV treatment), blocked with antigen-specific peptides; Lane 2: COS-7 cells (UV treatment); Lane 3: Hela cells (serum starvation treatment).
Product Details
PA5-104092
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RGS19(Accession P49795), corresponding to amino acid residues E125-H175.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853420
Product Specific Information
Antibody detects endogenous levels of total RGS19.
Target Information
RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium/calmodulin-dependent protein kinase I; G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19
Gene Aliases: 2610042F04Rik; AI324841; AW547781; Camki; GAIP; GNAI3IP; RGS19; RGSGAIP
UniProt ID: (Human) P49795, (Mouse) Q9CX84, (Rat) O70521
Entrez Gene ID: (Human) 10287, (Mouse) 56470, (Rat) 59293
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
positive regulation of GTPase activity
biological_process
regulation of G-protein coupled receptor protein signaling pathway
regulation of transcription, DNA-templated
autophagy
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
cell death
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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