Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
RGS2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 3
RGS2 Antibody (PA5-102486) in ICC/IF
Immunofluorescent analysis of RGS2 in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with RGS2 polyclonal antibody (Product # PA5-102486) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-102486
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RGS2(Accession P41220), corresponding to amino acid residues T36-E86.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2851888
Product Specific Information
Antibody detects endogenous levels of total RGS2.
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; regulator of G-protein signaling protein 2; RGS2
Gene Aliases: G0S8; GIG31; GOS8; RGS2
UniProt ID: (Human) P41220, (Rat) Q9JHX0, (Mouse) O08849
Entrez Gene ID: (Human) 5997, (Rat) 84583, (Mouse) 19735
regulation of translation
cell cycle
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of phospholipase activity
negative regulation of cardiac muscle hypertrophy
positive regulation of microtubule polymerization
negative regulation of MAP kinase activity
positive regulation of GTPase activity
negative regulation of cAMP-mediated signaling
negative regulation of G-protein coupled receptor protein signaling pathway
brown fat cell differentiation
relaxation of cardiac muscle
relaxation of vascular smooth muscle
positive regulation of cardiac muscle contraction
regulation of adrenergic receptor signaling pathway
biological_process
termination of G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway
negative regulation of signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support